VITAMIN C (Just to finish of from last week) Many lines of evidence suggest that oxidative stress, contributes to several aspects of endometriosis (Carvalho 2012; Augoulea 2012; Augoulea 2009; Gupta 2006; Sekhon 2013).
Therefore, it is not surprising that vitamins E and C, both of which possess considerable antioxidant properties, have been studied in the context of endometriosis.
In a study of 91 infertile women, those with endometriosis were shown to have lower levels of vitamin C in their follicular fluid (ie, fluid surrounding the eggs in the ovaries) compared to women who did not have endometriosis; women with endometriosis also had lower levels of the endogenous antioxidant superoxide dismutase in their plasma (Prieto 2012).
Other evidence suggests that lower intake of antioxidants, including vitamins E and C, selenium, and zinc, in women with endometriosis correlate with more severe disease (Hernandez Guerrero 2006).
These findings suggest that increasing consumption of antioxidants may benefit women with endometriosis. Accordingly, in a randomized, placebo-controlled trial, 59 women between 19 and 41 years of age were allocated to receive a combination of 1200 IU of vitamin E along with 1000 mg of vitamin C or a placebo each day for 8 weeks.
Following the 8-week treatment period, 43% of women who received the vitamin E and C combination experienced reduction in chronic pain, 37% experienced reduction in pain associated with menstruation, and 24% experienced reduction in pain during intercourse compared to the placebo group.